CA in 68%, peak response of FSH>LH by LHRH stimulating test in 90%. � The serum levels of PT and ICPP were all significantly higher than these of age- matched non-pubertal girls, without significant difference between PT and ICPP groups. Conclusion: girls aged 4~7 years with precocity of breast development mostly associated with other signs suspected of initiation of CPP which needs close survey. As leptin may well be a permisive factor for the initiation of sexual development, elevation of serum leptin level in PT girls may serve as early additive sign for evaluation of ICPP in occurrence. " v:shapes="_x0000_s1026">2361