LIPIDS METABOLISM IN
NEWBORNS AND INFANTS IN RELATION TO THE TYPE OF FEEDING
Pac-Kozuchowska
E, Chrzastek-Spruch H, Sadurska E
Department
of Paediatrics, Medical University School of Lublin, Poland
Objective: The aim of the study was the evaluation
of the type of feeding (breast-feeding, artificial, mixed) in newborns and
infants and the analysis of lipometabolism. The study included 161 newborns
and infants (95 boys, 66 girls) aged 2-22 weeks.
Methods: The concentration of triglicerides, total cholesterol
and HDL-chol was determined by means of Cormey set in Cobas-Mira S
apparatus, LDL-chol. and VLDL-chol by indirect method. Apo-A and Apo-B
assay was determined with Roche reagents.
Results: In the group of breast fed children the mean
values were as follows: triglicerides 141,66mg%, cholesterol 134,00mg%,
HDL-chol 35,68mg%, LDL-chol 69,02mg%, VLDL-chol 28,33mg%, Apo-A 146,82 mg%,
Apo-B 88,53mg%. In the group of artificially fed children:
triglicerides-127,40mg%, cholesterol 126,82mg%, HDL-chol 33,61mg%, LDL-chol
66,40mg%, VLDL-chol 25,48mg%, Apo-A 125,80mg%, Apo-B 67,19 mg%. In the
group of mix fed children: triglicerides 124,12 mg%, cholesterol 122,50
mg%, HDL-chol 30,09 mg%, LDL-chol 67,78 mg%, VLDL-chol 24,82mg%, Apo-A
124,52mg%, Apo-B 71,32mg%. The study confirmed higher values of total
cholesterol and its fractions and Apo-A and Apo-B in breast fed newborns
and infants. The level of Apo-A in children breast fed was only
significantly higher than in artificially and mix fed ones (p<0,05).
Conclusion: The study indicated that the type of
feeding since birth influences the behaviour of lipids metabolism.