0.05). But there were significant increases in the frequency of Gly16/Gly genogype in the severe asthma subgroup compared with the mild (0.67 vs 0.07, p<0.05), moderate subgroups (0.67 vs 0.12, p<0.05). Conclusions: The ��2-AR gene polymorphisms were not determinant of pathogenesis of asthma, but the b2-AR 16 locus polymorphisms is possibly correlated with asthmatic severity in the children of the Han nationality of southern China. " v:shapes="_x0000_s1026">1024