TRADITIONAL CHINESE MEDICINAL HERBS ��WEI
PING��GRANULE TREAT PEPTIC ULCERS IN CHILDREN
Chen Zh-D, Yan
H-M, Li S�CT, Yan R-J, Hou L-Y
Beijing
Children��s Hospital, Beijing, China
Objective: To evaluate the therapeutic effect of ��Wei Ping�� granule in peptic
ulcers with children.
Methods: All 98 children with peptic ulcers confirmed by flexible
gastroscopy in Beijing Children��s Hospital between June 1992 and December
1997. Detected Helicobacter pyloric (Hp) used rapid urease testing (RUT) on
gastric biopsy and biopsy specimens with Giemsa stain. All patients took
��Wei Ping�� granule orally over 4 weeks. After the therapy observe the
symptoms and physical signs to evaluate the curative effect. 65 children
were rechecked by gastroscopy, 76 children were followed-up after
discharge.
Result: 98 children (79 children with duodenal ulcers, 19 children with
gastric ulcers) were surveyed in this study. The clinical cure rate was
55.1%(54/98); improvement rate was 39.8%(39/98); ineffective rate was
5.1%(5/98); Total effective rate was 94.9%. To evaluate the curative effect
through gastroscopy: cure rate was 83.1%(54/65); improvement rate was
12.3%(8/65); ineffective rate was 4.6%(3/65); Total effective rate was
95.4%. The positive rate of Hp in peptic ulcers was 56.1%(55/98). After
therapy Hp eradication rate was 63.6%(35/55). 76 children were followed-up
after discharge, follow-up survey rate was 76.5%. Peptic ulcers recurrence
rate was 25.0%(19/76).
Conclusions: Traditional Chinese Medicine ��Wei ping���� granule improve the
curative effect and get lower recurrence rate in peptic ulcers.