THE CLINICAL SIGNIFICANCE OF THYROID
HORMONE IN CHILDREN OF NEPHROTIC SYNDROM
FENG
B, BAI X-Z, ZHANG W-S, LI S-L
The
First Medical College, Harbin Medical University, Harbin, China
Objective: To investigate the
changes of thyroid hormone (TH) abnormalities in nephrotic syndrome (NS),
the serum free tri-iodothyronine�
(FT3), free thyroxine (FT4) and
thyroid-stimulating hormone (TSH) levels were used to estimate the thyroid
function when there is some alteration in serum binding protein of NS.�
Methods: Examined the serum FT3,
FT4 and TSH of children of NS (n=30) were compared with control
groups, who were age-matched children (n=20).
Results: In control groups, a
significant decrease in FT3, FT4 (P<0.05) and
increase in the serum TSH concentration (p<0.05) in NS were observed. We
found that there was no relationship of the serum albumin or urinary
protein with the serum FT3, FT4 and TSH in NS.
Conclusion: The thyroid function have
a significant decrease in children of NS, so we may use the FT3 and FT4
level to judge the severity of NS, observe the therapeutic efficacy and
predict the prognosis.