0243

THE EFFECTS OF HIGH-FREQUENCY OSCILLATORY VENTILATION (HFOV) IN INFANTS WITH RESPIRATORY FAILURE

Wang L, Shen SH-Y

First Affiliated Hospital, XinJiang Medical University, Urumqi, China

Objective: To study the treatment of high-frequency oscillatory ventilation in infants with respiratory failure.

Methods: A total of 186 cases of neonates were selected during 1995-2000, were analyzed for changing in P_aO₂, P_aCO₂, S_aO₂, oxygenation index before HFOV treatment, 30 minutes and 12-16 hours following HFOV.

Results: 145 cases were cured in 186 cases, the cure rate was 77.96% and the mortality rate was 14.51%, in all the infants P_aO₂, S_aO₂ increased significantly (P<0.05) and P_aCO₂, oxygenation index decreased significantly (P<0.01), the complications included: respiratory bacterial infection, bronchopulmonary dysplasia (BPD), intracranial hemorrhage.

Conclusions: HFOV cause sustained improvement in systemic oxygenation, HFOV is effective treatment to severe respiratory failure.